2025 Week 10 · Final
Arizona Cardinals at Seattle Seahawks, final 22–44
Pregame first read
SEA run defense has the stronger league profile.
ARI run game #25/32 · SEA run defense #3/32 · 125 offense / 112 defense EPA plays.
Principal uncertainty · The model’s 80% range includes either team winning.
- Model spread
- SEA -4.5
- Model total
- 46
- 80% range (SEA margin)
- -8.8 to +24.6
League profiles describe different prior opponents. They do not measure this game’s head-to-head outcome. The model is a historical scoring estimate, not a betting line, and it does not know injuries or availability.
Recorded leaders
- PassingJacoby BrissettARI258 pass yds
- RushingZach CharbonnetSEA83 rush yds
- ReceivingTrey McBrideARI127 rec yds
Unit matchups
Rank among qualified teams by EPA per play, from each team's last five games before kickoff.
- SEA passing attack#2/32ARI pass defense#18/32
- SEA run game#28/32ARI run defense#17/32
- ARI passing attack#17/32SEA pass defense#14/32
- ARI run game#25/32SEA run defense#3/32
Players to watch
Per-game averages from 2025 games before kickoff, minimum two games. Availability is not verified.
ARIArizona Cardinals
- Kyler MurrayQB · 5 games192pass yds/g
- Trey BensonRB · 4 games40rush yds/g
- Marvin Harrison Jr.WR · 8 games61.5rec yds/g
- Trey McBrideTE · 8 games59.5rec yds/g
SEASeattle Seahawks
- Sam DarnoldQB · 8 games261pass yds/g
- Kenneth Walker IIIRB · 8 games59rush yds/g
- Jaxon Smith-NjigbaWR · 8 games119rec yds/g
- Cooper KuppWR · 7 games41.9rec yds/g