AUGRISOpen research

2025 Week 16 · Final

San Francisco 49ers at Indianapolis Colts, final 48–27

SFSFSan Francisco 49ers48INDINDIndianapolis Colts27

Pregame first read

SF passing attack has the stronger league profile.

SF passing attack #4/32 · IND pass defense #23/32 · 164 offense / 186 defense EPA plays.

Principal uncertainty · The model’s 80% range includes either team winning.

Model spread
SF -2.5
Model total
48
80% range (IND margin)
-16.8 to +17.3

League profiles describe different prior opponents. They do not measure this game’s head-to-head outcome. The model is a historical scoring estimate, not a betting line, and it does not know injuries or availability.

Recorded leaders

Unit matchups

Rank among qualified teams by EPA per play, from each team's last five games before kickoff.

  • IND passing attack#22/32SF pass defense#21/32
  • IND run game#20/32SF run defense#23/32
  • SF passing attack#4/32IND pass defense#23/32
  • SF run game#17/32IND run defense#4/32

Players to watch

Per-game averages from 2025 games before kickoff, minimum two games. Availability is not verified.

SFSan Francisco 49ers

INDIndianapolis Colts