2025 Week 4 · Final
Jacksonville Jaguars at San Francisco 49ers, final 26–21
Pregame first read
JAX run game has the stronger league profile.
JAX run game #9/32 · SF run defense #23/32 · 144 offense / 142 defense EPA plays.
Principal uncertainty · The model’s 80% range includes either team winning.
- Model spread
- JAX -1.5
- Model total
- 42.5
- 80% range (SF margin)
- -14.9 to +17.7
League profiles describe different prior opponents. They do not measure this game’s head-to-head outcome. The model is a historical scoring estimate, not a betting line, and it does not know injuries or availability.
Recorded leaders
- PassingBrock PurdySF309 pass yds
- RushingTravis EtienneJAX124 rush yds
- ReceivingChristian McCaffreySF92 rec yds
Unit matchups
Rank among qualified teams by EPA per play, from each team's last five games before kickoff.
- SF passing attack#7/32JAX pass defense#6/32
- SF run game#23/32JAX run defense#22/32
- JAX passing attack#18/32SF pass defense#16/32
- JAX run game#9/32SF run defense#23/32
Players to watch
Per-game averages from 2025 games before kickoff, minimum two games. Availability is not verified.
JAXJacksonville Jaguars
- Trevor LawrenceQB · 3 games224pass yds/g
- Travis EtienneRB · 3 games90rush yds/g
- Parker WashingtonWR · 2 games55rec yds/g
- Brenton StrangeTE · 3 games45.7rec yds/g
SFSan Francisco 49ers
- Mac JonesQB · 2 games282pass yds/g
- Christian McCaffreyRB · 3 games58.7rush yds/g
- Ricky PearsallWR · 3 games93.7rec yds/g
- Jauan JenningsWR · 2 games52.5rec yds/g