2025 Week 6 · Final
Arizona Cardinals at Indianapolis Colts, final 27–31
Pregame first read
IND pass defense has the stronger league profile.
ARI passing attack #19/32 · IND pass defense #4/32 · 178 offense / 190 defense EPA plays.
Principal uncertainty · The model’s 80% range includes either team winning.
- Model spread
- IND -3.5
- Model total
- 50.5
- 80% range (IND margin)
- -9.9 to +25.1
League profiles describe different prior opponents. They do not measure this game’s head-to-head outcome. The model is a historical scoring estimate, not a betting line, and it does not know injuries or availability.
Recorded leaders
- PassingJacoby BrissettARI320 pass yds
- RushingJonathan TaylorIND123 rush yds
- ReceivingZay JonesARI79 rec yds
Unit matchups
Rank among qualified teams by EPA per play, from each team's last five games before kickoff.
- IND passing attack#3/32ARI pass defense#18/32
- IND run game#3/32ARI run defense#3/32
- ARI passing attack#19/32IND pass defense#4/32
- ARI run game#22/32IND run defense#11/32
Players to watch
Per-game averages from 2025 games before kickoff, minimum two games. Availability is not verified.
ARIArizona Cardinals
- Kyler MurrayQB · 5 games192pass yds/g
- Trey BensonRB · 4 games40rush yds/g
- Marvin Harrison Jr.WR · 5 games61.2rec yds/g
- Trey McBrideTE · 5 games55rec yds/g
INDIndianapolis Colts
- Daniel JonesQB · 5 games258pass yds/g
- Jonathan TaylorRB · 5 games96rush yds/g
- Tyler WarrenTE · 5 games61.4rec yds/g
- Alec PierceWR · 3 games57rec yds/g