2026 Week 12 · Sun, Nov 29 · 4:25 PM ET
Seattle Seahawks at San Francisco 49ers
Matchup first read
SF run defense has the stronger league profile.
SEA run game #29/32 · SF run defense #2/32 · 142 offense / 118 defense EPA plays.
Principal uncertainty · The model’s 80% range includes either team winning.
- Model spread
- SEA -2.5
- Model total
- 45
- 80% range (SF margin)
- -17.2 to +16.8
League profiles describe different prior opponents. They do not measure this game’s head-to-head outcome. The model is a historical scoring estimate, not a betting line, and it does not know injuries or availability.
Unit matchups
Rank among qualified teams by EPA per play, from each team's last five games before kickoff.
- SF passing attack#10/32SEA pass defense#4/32
- SF run game#3/32SEA run defense#6/32
- SEA passing attack#24/32SF pass defense#20/32
- SEA run game#29/32SF run defense#2/32
Players to watch
Per-game averages from 2026 games before kickoff, minimum two games. Availability is not verified.
SEASeattle Seahawks
- Sam DarnoldQB · 6 games215pass yds/g
- Emanuel WilsonRB · 7 games57.6rush yds/g
- Jaxon Smith-NjigbaWR · 7 games124rec yds/g
- Cooper KuppWR · 7 games28.4rec yds/g
SFSan Francisco 49ers
- Brock PurdyQB · 7 games250pass yds/g
- Christian McCaffreyRB · 7 games55.6rush yds/g
- Mike EvansWR · 6 games70rec yds/g
- George KittleTE · 7 games60.7rec yds/g