2026 Week 16 · Fri, Dec 25 · 4:30 PM ET
Buffalo Bills at Denver Broncos
Matchup first read
BUF run game has the stronger league profile.
BUF run game #1/32 · DEN run defense #11/32 · 148 offense / 140 defense EPA plays.
Principal uncertainty · The model’s 80% range includes either team winning.
- Model spread
- BUF -1.5
- Model total
- 49
- 80% range (DEN margin)
- -16.6 to +17.4
League profiles describe different prior opponents. They do not measure this game’s head-to-head outcome. The model is a historical scoring estimate, not a betting line, and it does not know injuries or availability.
Unit matchups
Rank among qualified teams by EPA per play, from each team's last five games before kickoff.
- DEN passing attack#21/32BUF pass defense#29/32
- DEN run game#14/32BUF run defense#19/32
- BUF passing attack#5/32DEN pass defense#5/32
- BUF run game#1/32DEN run defense#11/32
Players to watch
Per-game averages from 2026 games before kickoff, minimum two games. Availability is not verified.
BUFBuffalo Bills
- Josh AllenQB · 6 games251pass yds/g
- James CookRB · 6 games105rush yds/g
- Dalton KincaidTE · 6 games52.5rec yds/g
- Khalil ShakirWR · 6 games48.3rec yds/g
DENDenver Broncos
- Bo NixQB · 7 games182pass yds/g
- Jonah ColemanRB · 2 games46.5rush yds/g
- Jaylen WaddleWR · 7 games39.4rec yds/g
- Pat BryantWR · 4 games33.3rec yds/g