AUGRISOpen research

2026 Week 18 · Sun, Jan 10 · 1:00 PM ET

San Francisco 49ers at Arizona Cardinals

SFSFSan Francisco 49ersARIARIArizona Cardinals

Matchup first read

SF run game has the stronger league profile.

SF run game #3/32 · ARI run defense #26/32 · 129 offense / 127 defense EPA plays.

Principal uncertainty · The model’s 80% range includes either team winning.

Model spread
SF -6.5
Model total
49.5
80% range (ARI margin)
-21.6 to +12.4

League profiles describe different prior opponents. They do not measure this game’s head-to-head outcome. The model is a historical scoring estimate, not a betting line, and it does not know injuries or availability.

Unit matchups

Rank among qualified teams by EPA per play, from each team's last five games before kickoff.

  • ARI passing attack#23/32SF pass defense#20/32
  • ARI run game#15/32SF run defense#2/32
  • SF passing attack#10/32ARI pass defense#30/32
  • SF run game#3/32ARI run defense#26/32

Players to watch

Per-game averages from 2026 games before kickoff, minimum two games. Availability is not verified.

SFSan Francisco 49ers

ARIArizona Cardinals